Use this space to discuss about SDL2. You can post and reply to the topics.
For a start, the SDL2 question ask your group to examine insulin effect on AD in a mouse model. Firstly, your group has to decide on the research question(s). For example, does insulin only affect cognition but not amyloid pathology? Or vice versa? Or both?
While ApoE4 is a strong genetic risk factor AD, you can choose if your group want to include this genetic element in your research question(s)? Whatever your group decides, please remember to choose the appropriate animal model to pursue your research question.